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Supported by a 2-year NSF grant, to discover the genes required to maintain the integrity of damaged mitochondrial DNA by homologous recombination and double-strand break repair. Specifically, work will focus on budding yeast mitochondria. Although mitochondria can repair double-strand breaks in their DNA, it is unknown how this is accomplished. Almost all genes needed for mitochondrial function are encoded in the nucleus, but repair in mitochondria does not employ any of the genes required to repair normal chromosomal beaks (e.g. Rad51, Rad52, etc). The project initially involves a CRISPRi-based search for genes that are required for homologous recombination and DSB repair in mitochondria.
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Requirements
PhD required. Experience in genetics and molecular biology. Experience working with budding yeast helpful, but is not required.
Job Information
- Job ID: 63390213
- Location:
Waltham, Massachusetts, United States - Position Title: Postdoc in DNA Repair, James Haber Lab
- Company Name For Job: Brandeis Univeristy
- Industry: Academia
- Job Function: Research
- Job Type: Full-Time
- Job Duration: 1-2 Years
- Min Education: Ph.D.
- Min Experience: 2-3 Years
- Required Travel: None
Please refer to the company's website or job descriptions to learn more about them.



